Hormonal control of glucose homoeostasis in ruminants
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چکیده
منابع مشابه
Hormonal control of glucose homoeostasis in ruminants.
Little, if any, glucose is absorbed from the alimentary tract of the grazing ruminant and it appears that significant absorption of glucose only occurs in ruminants consuming relatively large amounts of grain (Bergman, 1973 ; Lindsay, 1978). In spite of this, ruminants have an absolute requirement for glucose which is similar to that of nonruminants. Certainly glucose is an essential metabolite...
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Plasma glucose concentration is normally maintained within a narrow range despite wide fluctuations in the supply (meal) and demand (exercise) for nutrients. In adult humans, plasma glucose concentrations throughout a 24-hour period average 90 mg/ dl, with maximum values 60-90 minutes after meals, usually not exceeding 140 mg/ dl, and values during a moderate fast or exercise usually remaining ...
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The liver/islet high-K, facilitated glucose transporter (GLUT-2) and the glucose phosphorylating enzyme, glucokinase, are key regulators of the rate of glucose metabolism in liver and islets, the two ‘glucose-sensing’ tissues in mammals. Increases in circulating glucose stimulate insulin secretion from the ,%cells of the islets of Langerhans and convert the liver from an organ o f net glucose o...
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The association between liver disease and abnormalities of carbohydrate metabolism has long been recognized. Although other defects exist, disturbance of blood glucose homoeostasis is most commonly noted. Hypoglycaemia is a practical problem only in acute hepatitis and fulminant hepatic failure, when it is a direct manifestation of massive acute loss of normal hepatocellular function. Fasting h...
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Nuclear ubiquitous casein and cyclin-dependent kinase substrate (NUCKS) is highly expressed in the brain and peripheral metabolic organs, and regulates transcription of a number of genes involved in insulin signalling. Whole-body depletion of NUCKS (NKO) in mice leads to obesity, glucose intolerance and insulin resistance. However, a tissue-specific contribution of NUCKS to the observed phenoty...
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ژورنال
عنوان ژورنال: Proceedings of the Nutrition Society
سال: 1983
ISSN: 0029-6651,1475-2719
DOI: 10.1079/pns19830021